BDB557154

CD14 Mouse anti-Human, PE, Clone: M5E2, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB557154-Each-of-1 In Stock ₹ 15,548.30

BDB557154 - Each of 1

₹ 15,548.30

In Stock

Quantity

1

Base Price: ₹ 15,548.30

GST (18%): ₹ 2,798.694

Total Price: ₹ 18,346.994

Antigen

CD14

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human CD14 Protein

Quantity

50 Tests

Research Discipline

Immunology

Target Species

Cynomolgus, Rhesus Monkey

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

M5E2

Description

LPS receptor; LPS-R; Myeloid cell-specific leucine-rich glycoprotein

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The M5E2 monoclonal antibody specifically binds to CD14, a 53–55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein expressed at high levels on monocytes
  • Additionally, the anti-CD14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some Langerhans cells
  • CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB
  • This clone also cross-reacts with a major subset of peripheral blood monocytes on both rhesus and cynomolgus macaque monkeys
  • The pattern of reactivity on monocytes is weaker than that observed with peripheral blood monocytes from normal human donors
  • M5E2 reacts on non-human primate granulocytes and not on human granulocytes.