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BDB557357

CD45RC Rat anti-Mouse, PE, Clone: DNL-1.9, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB557357-Each-of-1 In Stock ₹ 23,318.00

BDB557357 - Each of 1

₹ 23,318.00

In Stock

Quantity

1

Base Price: ₹ 23,318.00

GST (18%): ₹ 4,197.24

Total Price: ₹ 27,515.24

Antigen

CD45RC

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

70Z/3 mouse pre-B cell line

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

DNL-1.9

Conjugate

PE

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The DNL-1.9 antibody reacts with an exon C-dependent epitope of CD45 protein which is found at high density on B cells, and at low density on peripheral T cytotoxic/suppressor cells, a subset of peripheral T helper cells, and a very small subset of thymocytes
  • CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family: Its intracellular (COOHterminal) region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated A, B, and C, respectively), plus differing levels of glycosylation
  • The CD45 isoforms detected in the mouse are cell type-, maturation-, and activation state-specific
  • The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.