BDB557593
MRP-1 Mouse anti-Human, FITC, Clone: QCRL-3, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB557593-Each-of-1 | In Stock | ₹ 25,632.00 |
BDB557593 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,632.00
GST (18%): ₹ 4,613.76
Total Price: ₹ 30,245.76
Antigen
MRP-1
Classification
Monoclonal
Conjugate
FITC
Host Species
Mouse
Quantity
100 Tests
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
QCRL-3
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- Reacts with an intracellular epitope of the multidrug resistance protein (MRP1)
- MRP1 is a 190kDa integral membrane phosphoglycoprotein, member of the ATP-binding cassette transporter proteins, overexpressed in some drug-selected resistant cell lines and has been shown to cause multidrug resistance in transfected cells
- Clone QCRL-3 was generated using non-denatured membranes from H69AR, an MRP1-overexpressing, multidrug resistant, drug-selected cell line
- Its epitope has been localized to the first nucleotide binding domain of MRP1 between amino acids 617 and 932.3 QCRL-3 does not cross-react with human MDR1 or MDR3 gene products, nor with murine MRP1
- It is reported that mAb QCRL-3 inhibits the ATP-dependent transport activity of MRP1 in inside-out membrane vesicles
- Host Species: Mouse Clone: QCRL-3 Isotype: IgG2a, κ Cross Reactivity: Human Flow Cytometry