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BDB557694

CD3 Mouse anti-Human, Alexa Fluor 488, Clone: UCHT1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB557694-Each-of-1 In Stock ₹ 33,108.00

BDB557694 - Each of 1

₹ 33,108.00

In Stock

Quantity

1

Base Price: ₹ 33,108.00

GST (18%): ₹ 5,959.44

Total Price: ₹ 39,067.44

Antigen

CD3

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

UCHT1

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Description

  • The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex
  • CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes
  • Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody
  • CD3 plays a central role in signal transduction during antigen recognition
  • The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.