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BDB557918

CD11b/Mac-1 Mouse anti-Human, Alexa Fluor 700, Clone: ICRF44, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB557918-Each-of-1 In Stock ₹ 33,642.00

BDB557918 - Each of 1

₹ 33,642.00

In Stock

Quantity

1

Base Price: ₹ 33,642.00

GST (18%): ₹ 6,055.56

Total Price: ₹ 39,697.56

Antigen

CD11b

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Mac-1α, integrin αM subunit, CR3 α chain

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

ICRF44

Conjugate

Alexa Fluor 700

Formulation

Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen

Human monocytes

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Description

  • The ICRF44 monoclonal antibody specifically binds to CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3
  • CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells
  • CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3)
  • This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP
  • This antibody conjugate is routinely tested by flow cytometry
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.