BDB558047
CD183 Mouse anti-Human, Alexa Fluor 488, Clone: 1C6/CXCR3, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558047-Each-of-1 | In Stock | ₹ 30,749.50 |
BDB558047 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,749.50
GST (18%): ₹ 5,534.91
Total Price: ₹ 36,284.41
Antigen
CD183
Classification
Monoclonal
Concentration
0.2mg/mL
Description
CXCR3; C-X-C chemokine receptor type 3; GPR9; IP10R; MigR; CKRL2; CMKAR3
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
1C6/CXCR3
Conjugate
Alexa Fluor 488
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Human CXCR3 Peptide
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- Clone 1C6/CXCR3 reacts with the human form of the 40 - 41kDa seven-transmembrane protein and member of the G protein-coupled receptor family
- CXCR3 is expressed primarily on activated T cells that infiltrate inflammatory sites
- It has also been detected on some circulating T cells, B cells, and NK cells
- Reports show that some CXCR3 T cells also express CCR5 and are mostly CD45RO cells
- Three ligands for CXCR3 have been identified
- They are interferon-γ inducible 10kDa protein (IP-10), monokine induced by interferon-γ (MIg), and interferon-inducible T-cell γ chemoattractant (I-TAC)
- These chemokines are produced by a variety of cells upon stimulation by IFN γ and interact with CXCR3 to mediate T-cell chemotaxis
- This reagent has been reported to be suitable for immunohistochemical staining of acetone-fixed, frozen sections and/or formalin-fixed, paraffin-embedded tissue sections with citrate pretreatment
- Clone CXCR3 also cross reacts with a subset of peripheral blood lymphocytes of baboon, and both rhesus and cynomolgus macaque monkeys
- The distribution of lymphocytes is similar to that observed with peripheral blood lymphocytes from normal human donors
- CXCR3 has been clustered as CD183 in the VIIth HLDA workshop
- This product is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
- Host Species: Mouse Clone: 1C6/CXCR3 Isotype: IgG1, κ Cross Reactivity: Human Flow Cytometry