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BDB558123

CD11b/Mac-1 Mouse anti-Human, Pacific Blue, Clone: ICRF44, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB558123-Each-of-1 In Stock ₹ 32,707.50

BDB558123 - Each of 1

₹ 32,707.50

In Stock

Quantity

1

Base Price: ₹ 32,707.50

GST (18%): ₹ 5,887.35

Total Price: ₹ 38,594.85

Antigen

CD11b

Classification

Monoclonal

Concentration

0.2mg/mL

Description

MAC-1A; Mac-1; ITGAM; Integrin alpha M; CR3A; CR-3 alpha; Mo1; SLEB6

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

ICRF44

Conjugate

Pacific Blue

Formulation

Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen

Human monocytes

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Description

  • The ICRF44 monoclonal antibody specifically binds to CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3
  • CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells
  • CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3)
  • This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.