Home Products Antibodies Primary Antibodies BDB558412
BDB558412

CD294 Rat anti-Human, Unlabeled, Clone: BM16, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB558412-Each-of-1 In Stock ₹ 14,596.00

BDB558412 - Each of 1

₹ 14,596.00

In Stock

Quantity

1

Base Price: ₹ 14,596.00

GST (18%): ₹ 2,627.28

Total Price: ₹ 17,223.28

Antigen

CD294

Classification

Monoclonal

Concentration

0.5mg/mL

Description

CRTH2; PTGDR2 ; Prostaglandin D2 receptor 2; DL1R; DP2; GPR44

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

BM16

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Transfectant cells

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Human

Isotype

IgG2a κ

Description

  • The BM16 monoclonal antibody specifically binds to CD294
  • CD294 is encoded by PTGDR2 (Prostaglandin D2 receptor 2) and is also known as CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells), GPR44 (G protein-coupled receptor 44), DL1R, and DP2
  • CD294 is a member of the G protein-coupled leukocyte chemoattractant receptor family and it is expressed on Th2, but not Th1 type cells
  • CD294 is detectable on CD4+ T cells in fresh PBMC but not on B cells and NK cells
  • CD294 is also expressed on peripheral blood basophils and eosinophils, suggesting its involvement allergic reactions
  • Phenotypic analysis of CD4+ T cells expressing CRTH2 demonstrated that they were also CD45RA-negative and CD45RO+ and CD25+
  • These cells produce Th2- but little or no Th1-type cytokines upon stimulation with PMA and Ionomycin.