BDB558453

CD267 Rat anti-Mouse, Alexa Fluor 647, Clone: 8F10, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB558453-Each-of-1 In Stock ₹ 23,095.50

BDB558453 - Each of 1

₹ 23,095.50

In Stock

Quantity

1

Base Price: ₹ 23,095.50

GST (18%): ₹ 4,157.19

Total Price: ₹ 27,252.69

Antigen

CD267

Classification

Monoclonal

Concentration

0.2mg/mL

Description

TACI

Host Species

Rat

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

8F10

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Rat RBL

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • Antibody 8F10 reacts with CD267 (TACI) a type III transmembrane protein receptor that binds to the ligands BAFF (BLyS), and APRIL
  • BAFF overproduction is associated with lupus erythematosus and Sjφgren's disease, two systemic autoimmune diseases
  • CD267 is expressed most notably on maturing subsets of splenic B cells such as transition type 2 (T2) and marginal zone (MZ) B cells and also in activated T-cells
  • In CD267 deficient mice, B cell numbers are increased and mice develop autoimmune disorders suggesting that CD267 plays a role in B cell regulation .