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BDB558821

CD140b Mouse anti-Human, PE, Clone: 28D4, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB558821-Each-of-1 In Stock ₹ 26,299.50

BDB558821 - Each of 1

₹ 26,299.50

In Stock

Quantity

1

Base Price: ₹ 26,299.50

GST (18%): ₹ 4,733.91

Total Price: ₹ 31,033.41

Antigen

CD140b

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

28D4

Description

PDGF Receptor β chain; PDGFRβ; PDGFRB; PDGFR1; PDGFR; PGFRB; JTK12

Host Species

Mouse

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG2a κ

Description

  • Reacts with platelet derived growth factor (PDGF) receptor β, a 170-190 kDa single transmembrane glycoprotein expressed on fibroblasts, smooth muscle cells, glial cells and chondrocytes
  • PDGF receptors, α and β, are single glycoproteinswith intracellular tyrosine kinase domains
  • They are structurally similar to M-CSF receptor and CD117 (c-kit)
  • Their ligand, PDGF, is a mitogen for connective tissue cells and glial cells
  • PDGF plays a role in wound healing and acts as a chemoattractant for fibroblasts, smooth muscle cells, glial cells, monocytes and neutrophils
  • Functional PDGF is secreted as a disulfide-linked dimer of A and B chains (PDGF-AA, PDGF-BB or PDGF-AB)
  • Binding of divalent PDGF induces receptor dimerization with three possible forms: αα, αβ, ββ
  • The PDGF receptor αβ and does not cross-react with PDGFRα.