BDB559370

CD80 Mouse anti-Human, PE-Cy5, Clone: L307.4, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB559370-Each-of-1 In Stock ₹ 33,241.50

BDB559370 - Each of 1

₹ 33,241.50

In Stock

Quantity

1

Base Price: ₹ 33,241.50

GST (18%): ₹ 5,983.47

Total Price: ₹ 39,224.97

Antigen

CD80

Classification

Monoclonal

Conjugate

PE-Cyanine5

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human B7-transfected L cells

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

L307.4

Description

B7.1; B7-1; Activation B7-1 antigen; B7; BB1; CD28LG; CD28LG1; LAB7

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • Reacts with B7/BB1, a 60kDa transmembrane glycoprotein which was clustered as CD80 in the Fifth International Workshop on Human Leukocyte Differentiation Antigens
  • CD80, a member of the Ig supergene family, is expressed on activated B cells, macrophages, and dendritic cells
  • It is the ligand for two molecules expressed on T cells, CD28 and CD152 (CTLA-4)
  • CD80 is also expressed on activated CD4+ and CD8+ T cells, appearing late after activation suggesting that activated T cells may be capable of autocrine costimulation via the CD28 activation pathway
  • The binding of CD28 by anti-CD28 or by CD80 results in T-cell activation and a signal for IL-2 production
  • Flow Cytometry