BDB560082
FoxP3 Mouse anti-Human, PE, Clone: 259D/C7, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560082-Each-of-1 | In Stock | ₹ 16,803.20 |
BDB560082 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,803.20
GST (18%): ₹ 3,024.576
Total Price: ₹ 19,827.776
Antigen
FoxP3
Classification
Monoclonal
Conjugate
PE
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
FoxP3 recombinant protein
Quantity
25 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
259D/C7
Description
Scurfin, IPEX, JM2
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype
IgG1
Related Products
Description
- The 259D/C7 antibody reacts with the human FoxP3 transcription factor, a member of the forkhead or winged helix family of transcription factors
- The expression of FoxP3, also known as Scurfin, IPEX and JM2, has been found to be associated with CD4+ regulatory T cells and represents a specific marker for these cells
- Flow-cytometric analysis has shown that FoxP3 is expressed by the majority of CD4+CD25+high T cells in peripheral blood while less than half of CD4+CD25int cell population are FoxP3 positive
- Approximately 5-10% of peripheral CD4+ cells are CD4+CD25+ T regulatory cells
- T regulatory cells are thought to play a critical role in the control of T cell mediated autoimmunity by suppressing the proliferation and cytokine production of other T cells
- To support this hypothesis, it has been found that FOXP3 is mutated in scurfy (sf) mice
- The 259D/C7 antibody reacts with all currently identified isoforms of human FoxP3 and is cross-reactive with Cynomolgus, Rhesus and Baboon.