BDB560306
Oct3/4 Mouse, Alexa Fluor 555, Clone: 40/OCT-3, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560306-Each-of-1 | In Stock | ₹ 45,924.00 |
BDB560306 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,924.00
GST (18%): ₹ 8,266.32
Total Price: ₹ 54,190.32
Antigen
OCT3/4
Classification
Monoclonal
Conjugate
Alexa Fluor 555
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen
Mouse Oct3 aa. 252-372 Recombinant Protein
Quantity
100 Tests
Research Discipline
Cell Biology
Target Species
Human, Mouse
Isotype
IgG1 κ
Applications
In vitro Assay
Clone
40/OCT-3
Description
Oct3, OTF3, Oct4, OTF4, POU5F1
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- Development of a multicellular organism from a single fertilized cell is regulated by the coordinated activity of DNA transcription factors
- Oct3/4, a member of the POU family of transcription factors, functions in pluripotent cells of early embryonic stem cell (ES) lines and embryonal carcinomas (EC)
- Other members of the POU family include Oct1, Oct2, Pit-1, and unc-86
- The POU domain, a 150-amino acid region that determines binding specificity, is conserved among these proteins and consists of 3 subdomains: POU-specific A and B subdomains and a homeobox-like subdomain
- Oct3/4 is expressed in undifferentiated cells, but is lost as cells are induced to differentiate
- Oct3/4 is not expressed in adult tissues
- The interaction of Oct3/4 with SOX2, another embryonic transcription factor, produces an active complex that regulates expression of genes such as Nanog, UTF1, and FGF4
- Although Oct3/4 is specifically phosphorylated on serine residues, this modification is not required for DNA binding, but may affect its transactivation potential
- Thus, Oct3/4 is a transcription factor that plays an important role in determining early steps of embryogenesis and differentiation
- Host Species: Mouse Clone: 40 Isotype: IgG1 κ Species Reactivity: Human Immunogen: Mouse Oct3 aa
- 252-372 Recombinant Protein Bioimaging