BDB560483
Nanog Mouse anti-Human, PE, Clone: N31-355, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560483-Each-of-1 | In Stock | ₹ 32,173.50 |
BDB560483 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,173.50
GST (18%): ₹ 5,791.23
Total Price: ₹ 37,964.73
Antigen
Nanog
Classification
Monoclonal
Conjugate
PE
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
N31-355
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human Nanog Recombinant Protein
Quantity
100 Tests
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- Description The N31-355 monoclonal antibody reacts with human Nanog (named for Tir Na Nog, the land of the ever-young of Celtic mythology), which is a homeobox transcription factor required for the maintenance of the undifferentiated state of pluripotent stem cells
- Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF (Leukemia Inhibitory Factor) and BMP (Bone Morphogenic Protein)
- When Nanog expression is down-regulated, cell differentiation can proceed
- Proteins that regulate Nanog expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53
- Nanog is one of the factors that can contribute to reprogramming of differentiated cells to an induced pluripotent stem cell state.