BDB560877
CD271 Mouse anti-Human, Alexa Fluor 647, Clone: C40-1457, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560877-Each-of-1 | In Stock | ₹ 14,658.30 |
BDB560877 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,658.30
GST (18%): ₹ 2,638.494
Total Price: ₹ 17,296.794
Antigen
CD271
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
C40-1457
Description
NGFR; NGF Receptor; TNFRSF16
Host Species
Mouse
Quantity
25 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The C40-1457 monoclonal antibody specifically recognizes CD271 that is also known as the nerve growth factor receptor (NGFR)
- CD271 is 75 kDa type I transmembrane glycoprotein likewise known as TNFRSF16 that belongs to the tumor necrosis factor receptor (TNFR) superfamily
- CD271 has been found localized to neuronal axons, Schwann cells, and perineural cells of peripheral nerves
- It is also expressed by some epithelial, mesenchymal and lymphoid tissues
- NGFR is the receptor for nerve growth factor (NGF), a polypeptide that is essential for normal development of the nervous system
- NGF promotes survival and differentiation of sympathetic and sensory neurons during embryological development of the peripheral nervous system
- NGF binds to two distinctive surface receptors, the p/140[prototrk] and p75[NGFR]
- High affinity binding of NGF requires that both receptor molecules be expressed
- NGFR is expressed on human and rat lymphocytes
- A subset of lymphoid cells in the spleen, lymph nodes, and follicular dendritic cells in germinal centers of reactive lymph nodes were found to express CD271
- It has been reported that NGFR interaction with its ligand, NGF, may play a role in immunoregulation
- NGF may also function as a B-cell growth factor.