BDB561025
CD4 Rat anti-Mouse, Alexa Fluor 700, Clone: RM4-5, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB561025-Each-of-1 | In Stock | ₹ 13,768.30 |
BDB561025 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 13,768.30
GST (18%): ₹ 2,478.294
Total Price: ₹ 16,246.594
Antigen
CD4
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
RM4-5
Conjugate
Alexa Fluor 700
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen
Mouse Thymocytes (BALB/c)
Quantity
25 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The RM4-5 monoclonal antibody specifically binds to the CD4 (L3T4) differentiation antigen expressed on most thymocytes, subpopulations of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells and immunosuppressive regulatory T cells), and a subset of NK-T cells
- CD4 has also been reported to be detected on pluripotent hematopoietic stem cells, bone marrow myeloid and B-lymphocyte precursors, intrathymic lymphoid precursors, and a subset of splenic dendritic cells
- CD4 has been reported to be expressed on the plasma membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm
- CD4 is an antigen coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells
- It participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck
- Purified RM4-5 mAb has been reported to block the binding of FITC-conjugated anti-mouse CD4 clones GK1.5 and H129.19, but not the RM4-4 clone
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.