BDB561156

SSEA-4 Mouse, V450, Clone: MC813-70, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB561156-Each-of-1 In Stock ₹ 25,765.50

BDB561156 - Each of 1

₹ 25,765.50

In Stock

Quantity

1

Base Price: ₹ 25,765.50

GST (18%): ₹ 4,637.79

Total Price: ₹ 30,403.29

Antigen

SSEA-4

Classification

Monoclonal

Conjugate

Violet Fluor 450 (V450)

Formulation

Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen

Human Teratocarcinoma Cell Line

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

MC813-70

Description

Stage-Specific Embryonic Antigen-4

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human, Mouse

Isotype

IgG3 κ

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Description

  • The MC813-70 monoclonal antibody reacts with S tage- S pecific E mbryonic A ntigen-4 (SSEA-4), a carbohydrate epitope on the major ganglioside, but not the neutral glycolipid, of human teratocarcinoma cells
  • As its name implies, the expression of SSEA-4 is stage-specific and can be used to characterize embryonic cells and monitor their differentiation
  • However, its expression pattern differs in the human and mouse
  • In the human, SSEA-4 is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (ICM), embryonic stem (ES) cells, and the K562 erythromyeloid leukeumia cell line
  • As human stem cells undergo differentiation, SSEA-4 expression is lost
  • In the mouse, SSEA-4 is found on oocytes and early cleavage-stage embryos, and primitive ectoderm, but not on EC, ICM, or ES cells
  • In some cases, SSEA-4 expression appears upon differentiation of mouse EC or ES cells
  • The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences
  • It is excited by the V iolet laser Ex max of 406nm and has an Em Max at 450 nm
  • Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.