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BDB561678

CD106 Rat anti-Mouse, FITC, Clone: 429 (MVCAM.A), BD

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 BDB561678-Each-of-1 In Stock ₹ 18,067.00

BDB561678 - Each of 1

₹ 18,067.00

In Stock

Quantity

1

Base Price: ₹ 18,067.00

GST (18%): ₹ 3,252.06

Total Price: ₹ 21,319.06

Antigen

CD106

Classification

Monoclonal

Concentration

0.5mg/mL

Description

Vcam-1; Vascular cell adhesion molecule 1; Vascular cell adhesion protein 1

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

429 (MVCAM.A)

Conjugate

FITC

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Mouse preadipose cell line PA6

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2a κ

Description

  • The 429 monoclonal antibody specifically binds to both the long (∼110 kDa) transmembrane-spanning form and the truncated (∼47 kDa) GPI-linked form of vascular cell adhesion molecule-1 (VCAM-1, CD106)
  • CD106 is constitutively expressed on bone marrow stromal cells, myeloid cells, and splenic dendritic cells
  • Its expression on endothelial cells is upregulated by inflammatory cytokines and in certain pathologic conditions
  • CD106 expression has also been detected on apoptotic thymocytes, splenocytes, and lymphoid cell lines
  • VCAM-1 is a counter-receptor for VLA-4 ( α;4 β; 1 integrin) and LPAM-1 ( α;4 β; 7 integrin), and the 429 antibody partially blocks VCAM-1-mediated binding functions
  • Source of the immunogen was the mouse preadipose cell line PA6.