BDB561682

CD117 Mouse anti-Human, PE, Clone: YB5.B8, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB561682-Each-of-1 In Stock ₹ 12,335.40

BDB561682 - Each of 1

₹ 12,335.40

In Stock

Quantity

1

Base Price: ₹ 12,335.40

GST (18%): ₹ 2,220.372

Total Price: ₹ 14,555.772

Antigen

CD117

Classification

Monoclonal

Concentration

0.2mg/mL

Description

KIT; c-Kit; SCFR; PBT; Mast/stem cell growth factor receptor

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

YB5.B8

Conjugate

PE

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Acute myelocytic leukemia blasts

Quantity

25 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The YB5.B8 monoclonal antibody specifically binds to CD117
  • CD117, also known as c-Kit, is a 145 kDa cell-surface glycoprotein with tyrosine kinase activity
  • CD117 is present on hematopoietic progenitor cell subsets, thymocytes, mast cells, hepatocytes and histiocytes
  • CD117 serves as a cytokine receptor for steel factor (SLF), also known as stem cell factor (SCF) or mast cell growth factor (MGF)
  • The interaction of c-Kit and SLF is crucial to hematopoiesis, mast cell differentiation, melanogenesis, and germ cell development
  • The ability of the YB5.B8 antibody to block the binding of c-Kit ligand is still controversial.