BDB561704

CD138 Mouse anti-Human, PE, Clone: MI15, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB561704-Each-of-1 In Stock ₹ 11,445.40

BDB561704 - Each of 1

₹ 11,445.40

In Stock

Quantity

1

Base Price: ₹ 11,445.40

GST (18%): ₹ 2,060.172

Total Price: ₹ 13,505.572

Antigen

CD138

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human U266 and XG-1 Myeloma Cell Lines

Quantity

25 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

MI15

Description

Syndecan; SDC; Syndecan 1; SDC1; SYND1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The MI15 monoclonal antibody specifically binds to CD138 (Syndecan-1), an 85-92 kDa single chain transmembrane protein, strongly expressed on multiple-myeloma-derived cell lines and malignant plasma cell populations
  • It is also expressed on pre-B cells, immature B cells, and plasma cells, but not on mature circulating B-lymphocytes
  • Syndecan-1 is a member of the family of transmembrane heparan sulfate proteoglycans
  • It is also expressed on some non-hematopoietic cells, including embryonic mesenchymal cells, vascular smooth muscle cells, endothelial and neural cells
  • CD138 binds to many extracellular matrix proteins through its heparan sulfate side-chains, like fibronectin, collagen types I, III, and V, tenascin, thrombospondin, and antithrombin III
  • It is considered an extracellular matrix receptor that may serve as a co-receptor for fibroblast growth factor and related molecules
  • Monoclonal antibody MI15 blocks the binding of clone B-B4 but not clone DL-101 (other anti-syndecan-1 antibodies) by flow cytometric analysis
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.