BDB561922

CD62P Mouse anti-Human, FITC, Clone: AK-4, BD

Manufacturer: Fischer Scientific

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Antigen

CD62P

Classification

Monoclonal

Conjugate

FITC

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

AK-4

Description

P-Selectin; GMP-140; PADGEM

Host Species

Mouse

Quantity

25 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The AK-4 monoclonal antibody specifically binds to CD62P
  • CD62P is a 140 kDa type I transmembrane glycoprotein that is also known as P-Selectin, Platelet activation-dependent granule membrane protein (PADGEM), or GMP-140
  • P-Selectin is stored in the α -granules of platelets and the Weibel-Palade bodies of endothelial cells, and is rapidly transported to the plasma membrane upon activation
  • P-Selectin is thought to mediate the initial adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses, and of activated platelets to neutrophils and monocytes in hemostasis.