BDB561975
CD95 Mouse anti-Human, FITC, Clone: DX2, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB561975-Each-of-1 | In Stock | ₹ 12,282.00 |
BDB561975 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,282.00
GST (18%): ₹ 2,210.76
Total Price: ₹ 14,492.76
Antigen
CD95
Classification
Monoclonal
Conjugate
FITC
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human CD95-transfected L Cells
Quantity
25 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
DX2
Description
APO-1; FAS; TNFRSF6; APT1; ALPS1A; FAS1; FASTM; FASLG receptor
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Baboon, Canine, Cynomolgus, Human, Porcine, Rhesus Monkey
Isotype
IgG1 κ
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Description
- The DX2 monoclonal antibody specifically binds to the human Fas antigen (also called APO-1)
- This 45 kDa transmembrane cell surface molecule was designated as CD95 at the Fifth HLDA Workshop
- Fas is a member of the TNF-receptor superfamily and is also known as Tumor necrosis factor receptor superfamily member 6 (TNFRSF6)
- It is expressed on a variety of normal and neoplastic cells including activated T and B lymphocytes and some undifferentiated thymocytes
- The Fas/CD95 antigen is a polypeptide that plays a role in the programmed sequence of events leading to cell death, termed apoptosis
- The DX2 clone specifically reacts with murine L cells, murine L1210 leukemia cells and murine P815 mastocytoma cells transfected with human Fas cDNA but not with untransfected parental cell lines
- Crosslinking CD95 with DX2 antibody delivers an apoptotic signal indicating that DX2 recognizes a functional epitope of the CD95 antigen
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.