BDB562100

Disialoganglioside GD2 Mouse anti-Human, PE, Clone: 14.G2a, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562100-Each-of-1 In Stock ₹ 22,962.00

BDB562100 - Each of 1

₹ 22,962.00

In Stock

Quantity

1

Base Price: ₹ 22,962.00

GST (18%): ₹ 4,133.16

Total Price: ₹ 27,095.16

Antigen

Disialoganglioside GD2

Classification

Monoclonal

Conjugate

PE

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a

Applications

Flow Cytometry

Clone

14.G2a

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

LAN-1 human neuroblastoma cells

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • Gangliosides are sialic-acid bearing glycolipids that are expressed on the surface of all mammalian cells, and are likely involved in mediating cell-substratum interactions
  • They are important target antigens for antibody dependent cellular cytotoxicity (ADCC) of human melanoma and neuroblastoma cells
  • Human melanoma cells produce gangliosides, designated as GD2 and GD3 which are deposited in the subtratum-attached material, and may play a significant role in the melanoma metastatic phenotype
  • Clone 14.G2a specifically reacts with human and mouse GD2 ganglioside
  • LAN-1 human neuroblastoma cells were used as immunogen
  • Clone 14.G2a is an isotype switch variant selected from the parental IgG3-producing hybridoma 14.18 and has identical reactivity as the parental antibody
  • Clone 14.G2a is routinely tested by flow cytometry using M21 human melanoma cells.