BDB562101
Nkp46 Mouse anti-Human, PE-Cy7, Clone: 9E2/NKp46 (also known as 9-E2), BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562101-Each-of-1 | In Stock | ₹ 21,627.00 |
BDB562101 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 21,627.00
GST (18%): ₹ 3,892.86
Total Price: ₹ 25,519.86
Antigen
Nkp46
Classification
Monoclonal
Conjugate
PE-Cyanine7
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human NKp46 Recombinant Protein
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
9E2/NKp46 (also known as 9-E2)
Description
NCR1; NK-p46; hNKp46; LY94; Natural cytotoxicity triggering receptor 1
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The 9E2/Nkp46 monoclonal antibody specifically binds to CD335
- CD335 is also known as the Natural killer cell p46-related protein (NKp46) and the Natural cytotoxicity triggering receptor 1 (NCR1)
- CD335 is a 46 kDa type I membrane glycoprotein that is expressed on resting and activated NK cells
- Its extracellular region contains two C2-type, Ig-like domains
- The transmembrane domain contains a positively charged amino acid (Arg) which could be involved in stabilizing the association with CD3ζ
- Its intracellular region does not contain immunoreceptor tyrosine-based activating motifs (ITAM), but it is linked to intracytoplasmic transduction machinery by its association with CD3ζ and FcεRIγadaptor proteins
- CD335 along with NKp30 and NKp44 are referred to as natural cytotoxicity receptors (NCR)
- These receptors play very important roles in cells that kill virus-infected target cells, tumor cells and MHC-class I-unprotected cells.