BDB562408

CD105 Mouse anti-Human, APC, Clone: 266, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562408-Each-of-1 In Stock ₹ 20,025.00

BDB562408 - Each of 1

₹ 20,025.00

In Stock

Quantity

1

Base Price: ₹ 20,025.00

GST (18%): ₹ 3,604.50

Total Price: ₹ 23,629.50

Antigen

CD105

Classification

Monoclonal

Conjugate

APC

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human Umbilical Vein Endothelial Cells

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

266

Description

Endoglin; ENG; END; HHT1; ORW; ORW1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The 266 monoclonal antibody specifically binds to CD105
  • CD105 presents an integral membrane homodimer protein with subunits of 95 kDa found on vascular endothelial cells and syncytiotrophoblasts of placenta
  • CD105 is weakly expressed on stromal fibroblasts
  • It is also expressed on U937 cells, activated macrophages, and mesenchymal stem cells
  • CD105 is a component of the TGF-β receptor system in human umbilical vein endothelial cells and binds TGF-β1 and TGF-β3 with high affinity but does not bind toTGF-β2
  • Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation.