BDB562420

CD45 Rat anti-Mouse, PE-CF594, Clone: 30-F11, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562420-Each-of-1 In Stock ₹ 33,464.00

BDB562420 - Each of 1

₹ 33,464.00

In Stock

Quantity

1

Base Price: ₹ 33,464.00

GST (18%): ₹ 6,023.52

Total Price: ₹ 39,487.52

Antigen

CD45

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Ptprc; CD45R; LCA; Leukocyte common antigen; T200; B220; Ly-5; Lyt-4

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

30-F11

Conjugate

PE-CF594

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Mouse Thymus / Spleen

Quantity

0.1 mg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 30-F11 clone has been reported to react with all isoforms and both alloantigens of CD45, which is found on hematopoietic stem cells and all cells of hematopoietic origin, except erythrocytes
  • CD45 is a transmembrane glycoprotein which is expressed at high levels on the cell-surface, and its presence distinguishes leukocytes from non-hematopoietic cells
  • CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family, where the intracellular carboxy-terminal region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated as A, B, and C, respectively)
  • CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction and the CD45 isoforms detected in the mouse are cell type-, maturation-, and activation state-specific
  • This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™
  • PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics
  • Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20-nm filter).