BDB562445

CD38 Mouse anti-Human, Brilliant Violet 421, Clone: HIT2, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562445-Each-of-1 In Stock ₹ 19,135.00

BDB562445 - Each of 1

₹ 19,135.00

In Stock

Quantity

1

Base Price: ₹ 19,135.00

GST (18%): ₹ 3,444.30

Total Price: ₹ 22,579.30

Antigen

CD38

Classification

Monoclonal

Conjugate

Brilliant Violet 421

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

HIT2

Description

T10; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1

Host Species

Mouse

Quantity

25 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The HIT2 monoclonal antibody specifically binds to CD38
  • CD38 is a 45 kDa type II single-chain transmembrane glycoprotein present on thymocytes, activated T cells and terminally differentiated B cells (plasma cells)
  • Other reactive cells include monocytes, macrophages, dendritic cells and some epithelial cells
  • The CD38 antigen acts as an ectoenzyme that catalyzes the synthesis and hydrolysis of a Ca++ mobilizing agent, cyclic ADP-ribose
  • This intracellular calcium plays an important role in cell signaling pathways
  • Reports describe CD38 as participating in adhesion with CD31, immunoregulatory functions involving signal transduction leading to cell growth, apoptosis, and differentiation
  • The antibody was conjugated to Brilliant Violet 421 and has been developed in collaboration with Sirigen
  • With an Ex Max of 407-nm and Em Max at 421-nm, Brilliant Violet 421 can be excited by the violet laser and detected in the standard Pacific Blue filter set (eg, 450/50-nm filter)
  • Brilliant Violet 421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates
  • Host Species: Mouse Clone: HIT2 Isotype: IgG1, κ Species Reactivity: Human Flow Cytometry