BDB562783

TNF Mouse anti-Human, Brilliant Violet 421, Clone: Mab11, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562783-Each-of-1 In Stock ₹ 27,234.00

BDB562783 - Each of 1

₹ 27,234.00

In Stock

Quantity

1

Base Price: ₹ 27,234.00

GST (18%): ₹ 4,902.12

Total Price: ₹ 32,136.12

Antigen

TNF

Classification

Monoclonal

Conjugate

Brilliant Violet 421

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Recombinant Human TNF

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

Mab11

Description

Tumor necrosis factor alpha; TNF-a; TNF-α; TNFSF2; Cachectin

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The MAb11 monoclonal antibody specifically binds to human tumor necrosis factor (TNF, also known as TNF-α) protein
  • TNF is an efficient juxtacrine, paracrine and endocrine mediator of inflammatory and immune functions
  • It regulates the growth and differentiation of a variety of cell types
  • TNF is cytotoxic for transformed cells when in conjunction with IFN-γ
  • It is secreted by activated monocytes/macrophages and other cells such as B cells, T cells and fibroblasts
  • The immunogen used to generate the MAb11 hybridoma was recombinant human TNF
  • The MAb11 antibody has been reported to crossreact with Rhesus Macaque TNF
  • The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
  • With an Ex Max of 407nm and Em Max at 421nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter)
  • BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates
  • Host Species: Mouse Clone: Mab11 Isotype: IgG1, κ Species Reactivity: Hu Immunogen: Recombinant Human TNF Flow Cytometry, Intracellular Staining