BDB562920

CD69 Hamster anti-Mouse, Brilliant Violet 421, Clone: H1.2F3, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562920-Each-of-1 In Stock ₹ 24,208.00

BDB562920 - Each of 1

₹ 24,208.00

In Stock

Quantity

1

Base Price: ₹ 24,208.00

GST (18%): ₹ 4,357.44

Total Price: ₹ 28,565.44

Antigen

CD69

Classification

Monoclonal

Concentration

0.2mg/mL

Description

VEA; Very Early Activation Antigen; AIM; Activation Induced Molecule

Host Species

Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 λ

Applications

Flow Cytometry

Clone

H1.2F3

Conjugate

Brilliant Violet 421

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Mouse Dendritic Epidermal T Cell Line Y245

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The H1.2F3 monoclonal antibody specifically binds to CD69 (Very Early Activation antigen), an 85 kDa disulfide-linked homodimer of differentially glycosylated subunits
  • CD69 is a C-type lectin, most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules
  • Its expression is rapidly induced upon activation of lymphocytes (T, B, NK, and NK-T cells), neutrophils, and macrophages
  • CD69 is expressed also on thymocytes that are undergoing positive selection; its role in that process is unclear
  • H1.2F3 mAb augments PMA-induced T-cell stimulation and IFN-γ-induced macrophage stimulation
  • IL-2-activated NK cells express CD69, and H1.2F3 mAb induces redirected lysis of FcR-bearing target cells by NK cells
  • The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
  • With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter)
  • BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.