BDB562945
CD52 Mouse anti-Human, PE, Clone: 4C8, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562945-Each-of-1 | In Stock | ₹ 17,622.00 |
BDB562945 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,622.00
GST (18%): ₹ 3,171.96
Total Price: ₹ 20,793.96
Antigen
CD52
Classification
Monoclonal
Conjugate
PE
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen
Human T Lymphocytes
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
4C8
Description
Cambridge pathology 1 Ag; CAMPATH-1; Epididymal secretory protein E5; HE5
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG3 κ
Related Products
Description
- The 4C8 monoclonal antibody specifically binds to CD52 which is also known as Cambridge pathology 1 antigen (CAMPATH-1) or Human epididymis-specific protein 5 (HE5)
- CD52 is a highly N-glycosylated, 25-29 kDa protein whose C-terminus is glycophosphatidylinositol anchored in the membrane
- It is highly expressed on the surface of thymocytes and mature lymphocytes but not on their stem cell precursors
- It is also expressed on monocytes, dendritic cells, eosinophils and epithelial cells of the epididymis and seminal vesicles but not on neutrophils, plasma cells, platelets or erythrocytes
- Although its functional role is not well characterized, the CD52 antigen serves as an exquisitely sensitive target antigen for antibody and complement-mediated lysis of CD52-positive cells
- Anti-CD52 antibodies are being used clinically to remove lymphocytes from transplanted bone marrow cell preparations and in the treatment of some malignant diseases.