BDB563022

Nkx6.1 Mouse, Unlabeled, Clone: R11-560, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB563022-Each-of-1 In Stock ₹ 31,639.50

BDB563022 - Each of 1

₹ 31,639.50

In Stock

Quantity

1

Base Price: ₹ 31,639.50

GST (18%): ₹ 5,695.11

Total Price: ₹ 37,334.61

Antigen

Nkx6.1

Classification

Monoclonal

Concentration

0.5mg/mL

Description

Nkx6.1, NKX6-1, NKX6A, Nkx6-1, Nkx6.1, Nkx6a

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human, Mouse

Isotype

IgG1 κ

Applications

Western Blot

Clone

R11-560

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human Nkx6.1 Recombinant Protein

Quantity

100 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • Description The R11-560 monoclonal antibody specifically binds to human and mouse homeobox protein Nkx6.1
  • The transcription factor Nkx6.1 plays a role in pancreatic islet beta cell development through the regulation of HNF1a and insulin genes
  • Nkx6.1 is considered to be a highly specific transcription factor marking pancreatic beta islet cells, where it is expressed in both developing and mature cells
  • In addition, Nkx6.1 functions as a transcriptional repressor induced by the Sonic Hedgehog (Shh) signaling pathway in fate determination of several neuronal cell types
  • During antibody development, the purified R11-560 monoclonal antibody was found to detect Nkx6.1 by western blot and indirect immunofluorescent staining followed by flow cytometric analysis or imaging analysis.