BDB563081
RORγt Mouse anti-Human, PE, Clone: Q21-559, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563081-Each-of-1 | In Stock | ₹ 25,409.50 |
BDB563081 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,409.50
GST (18%): ₹ 4,573.71
Total Price: ₹ 29,983.21
Antigen
RORγt
Classification
Monoclonal
Conjugate
PE
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human RORγt Recombinant Protein
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
Q21-559
Description
RORgt; ROR gamma t; RORC; NR1F3; RORG; RZRG; TOR; RZR-GAMMA
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2b κ
Related Products
Description
- Description The Q21-559 monoclonal antibody recognizes ROR gamma t (RORγt), an isoform of RORgamma (RORγ)
- RORγt is a DNA-binding transcription factor that is encoded by the RORC (RAR-related orphan receptor C) gene
- It belongs to the ROR/RZR orphan nuclear receptor family
- Two protein isoforms are produced from the RORC gene by alternative splicing: RORγγt is highly restricted to the thymus where it is expressed exclusively in immature CD4+CD8+ thymocytes and in peripheral Th17 and LTi cells
- RORγt reportedly functions as an essential transcription factor for the development of secondary lymphoid tissues
- It also plays an important regulatory role in thymopoiesis and effector T cell differentiation, especially for Th17 cells.