BDB563360

CD62E Mouse anti-Human, Brilliant Violet 421, Clone: 68-5H11, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB563360-Each-of-1 In Stock ₹ 42,542.00

BDB563360 - Each of 1

₹ 42,542.00

In Stock

Quantity

1

Base Price: ₹ 42,542.00

GST (18%): ₹ 7,657.56

Total Price: ₹ 50,199.56

Antigen

CD62E

Classification

Monoclonal

Conjugate

Brilliant Violet 421

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

68-5H11

Description

SELE; E-selectin; Selectin E; ELAM; ELAM1; ESEL; LECAM2

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 68-5H11 monoclonal antibody specifically binds to CD62E
  • This adhesion molecule is a 97-115 kDa type I transmembrane glycoprotein that is encoded by the SELE gene
  • CD62E is also known as E-selectin, Endothelial-leukocyte adhesion molecule-1 (ELAM-1), and Leukocyte endothelial cell adhesion molecule 2 (LECAM-2)
  • CD62E is minimally expressed by unstimulated endothelium
  • Activated endothelial cells upregulate surface CD62E expression in response to various activators including inflammatory cytokines such as Interleukin-1 and Tumor Necrosis Factor
  • CD62E plays a role in leucocyte extravasation by promoting leucocyte rolling on activated endothelial cells during inflammation
  • CD62E may also play a role in the metastasis of certain tumor cells
  • The adhesion between endothelial CD62E molecules and a carbohydrate ligand on neutrophils is inhibited by the mAb 68-5H11.