BDB563473

CD134 Mouse anti-Human, APC, Clone: ACT35, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB563473-Each-of-1 In Stock ₹ 16,198.00

BDB563473 - Each of 1

₹ 16,198.00

In Stock

Quantity

1

Base Price: ₹ 16,198.00

GST (18%): ₹ 2,915.64

Total Price: ₹ 19,113.64

Antigen

CD134

Classification

Monoclonal

Conjugate

APC

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human HUT 102

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

ACT35

Description

OX40; TNFRSF4; TXGP1L; OX40L Receptor

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The ACT35 monoclonal antibody specifically binds to CD134 which is also known as OX40
  • The 35 kDa CD134 polypeptide is encoded by the TNFRSF4 gene
  • CD134 is a type I integral membrane glycoprotein and member of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family
  • CD134 is expressed on activated T lymphocytes, hematopoietic precursor cells and fibroblasts
  • CD134 functions as a T cell costimulatory receptor when bound by OX40 Ligand/TNFSF4 that is expressed by antigen presenting cells
  • CD134 thereby plays roles in T-cell activation as well as the regulation of differentiation, proliferation or apoptosis of normal and malignant lymphoid cells
  • Analysis of the nucleotide sequence of the human TNFRSF4 cDNA reveals strong homology with the rat Tnfrsf4 cDNA sequence
  • OX40 was clustered as CD134 in the Sixth International Workshop on Human Leukocyte Differentiation Antigens.