BDB563585

CD47 Rat anti-Mouse, PE, Clone: miap301, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB563585-Each-of-1 In Stock ₹ 12,282.00

BDB563585 - Each of 1

₹ 12,282.00

In Stock

Quantity

1

Base Price: ₹ 12,282.00

GST (18%): ₹ 2,210.76

Total Price: ₹ 14,492.76

Antigen

CD47

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Cd47; IAP; Integrin-associated protein; Itgp

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

miap301

Conjugate

PE

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Not reported

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The miap301 monoclonal antibody specifically binds to the extracellular domain of CD47, also known as Integrin-Associated Protein (IAP)
  • CD47 is a 50-kDa plasma membrane protein with an extracellular immunoglobulin variable region-like domain, a multiple membrane-spanning segment, and a short C-terminal cytoplasmic tail
  • IAP is often physically associated with β3 integrins, and it may act as a transducer element in activation mediated by these integrins
  • CD47 is expressed by a wide variety of cell types, including some cells lacking integrins, such as erythrocytes
  • The cytoplasmic tail region is expressed as alternatively spliced forms, which are differentially expressed in diverse tissues, suggesting that IAP may have distinct functions in various tissues
  • CD47 and its ligand, CD172a, are proposed to mediate bi-directional signaling to modify neural synaptic activity and regulate the phagocytic activities of macrophages.