BDB563632
CD77 Mouse anti-Human, Alexa Fluor 647, Clone: 5B5, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563632-Each-of-1 | In Stock | ₹ 31,639.50 |
BDB563632 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,639.50
GST (18%): ₹ 5,695.11
Total Price: ₹ 37,334.61
Antigen
CD77
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen
Initially Adherent Human Peripheral Blood Cells
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
5B5
Description
BLA; Gb3; Pk blood group antigen; CTH
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgM κ
Related Products
Description
- The 5B5 monoclonal antibody specifically binds to human CD77, a small neutral glycosphingolipid also referred to as globotriaosylceramide (Gb3), Burkitt 's lymphoma associated antigen (BLA), ceramide trihexoside (CTH), and Pk blood group antigen
- CD77 is expressed on a subset of germinal center B-lymphocytes including centroblasts that are found with greater frequency in tonsil and mucosal lymphoid tissues and less frequently in peripheral blood, bone marrow and spleen
- It has been described as a receptor for Shiga Toxin, produced by Shigella dysenteriae , and Verotoxin 1 (VT1), produced by some strains of E
- coli
- CD19 has been reported as a ligand for CD77
- This interaction may function in adhesion and signal transduction at a specific stage of B cell differentiation
- Studies have shown that cross-linking CD77 induces apoptosis in some B cell lines.