BDB563817
SSEA-4 Mouse, BUV395, Clone: MC813-70, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563817-Each-of-1 | In Stock | ₹ 31,995.50 |
BDB563817 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,995.50
GST (18%): ₹ 5,759.19
Total Price: ₹ 37,754.69
Antigen
SSEA-4
Classification
Monoclonal
Conjugate
Brilliant Ultraviolet 395
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human Teratocarcinoma Cell Line
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
MC813-70
Description
Stage-Specific Embryonic Antigen-4
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human, Mouse
Isotype
IgG3 κ
Related Products
Description
- The MC813-70 monoclonal antibody reacts with S tage- S pecific E mbryonic A ntigen- 4 (SSEA-4), a carbohydrate epitope on the major ganglioside, but not the neutral glycolipid, of human teratocarcinoma cells
- As its name implies, the expression of SSEA-4 is stage-specific and can be used to characterize embryonic cells and monitor their differentiation
- However, its expression pattern differs in the human and mouse
- In the human, SSEA-4 is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (ICM), embryonic stem (ES) cells, and the K562 erythromyeloid leukeumia cell line
- As human stem cells undergo differentiation, SSEA-4 expression is lost
- In the mouse, SSEA-4 is found on oocytes and early cleavage-stage embryos, and primitive ectoderm, but not on EC, ICM, or ES cells
- In some cases, SSEA-4 expression appears upon differentiation of mouse EC or ES cells
- The antibody was conjugated to BD Horizon™ BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument
- With an Ex Max at 348 nmand an Em Max at 395nm, this dye has virtually no spillover into any other detector
- BD Horizon™ BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.