BDB564010
CD3 Molecular Complex Rat anti-Mouse, Brilliant Violet 786, Clone: 17A2, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564010-Each-of-1 | In Stock | ₹ 27,367.50 |
BDB564010 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,367.50
GST (18%): ₹ 4,926.15
Total Price: ₹ 32,293.65
Antigen
CD3 Molecular Complex
Classification
Monoclonal
Concentration
0.2mg/mL
Description
CD3; CD3 epsilon; Cd3e; CD3ε; T3e
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2b κ
Applications
Flow Cytometry
Clone
17A2
Conjugate
Brilliant Violet 786
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
γ δ TCR-positive T-T hybridoma D1
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The 17A2 monoclonal antibody specifically binds to the T-cell receptor-associated CD3 complex that is expressed on many thymocytes and mature T lymphocytes
- Plate-bound 17A2 antibody has been reported to induce IL-2 production by cultured T cells in the absence of accessory cells
- The binding of the 17A2 antibody to T cells can be blocked by the anti-CD3e mAb 145-2C11
- This suggests that the 17A2 antibody recognizes an epitope of the CD3 epsilon chain
- In vivo treatment with 17A2 antibody has been reported to partially deplete T lymphocytes and temporarily down-modulates CD3 expression on T cells
- The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
- This dye is a tandem fluorochrome of BD Horizon™ BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm
- BD Horizon™ BV786 can be excited by the violet laser and detected in a filter used to detect Cy7™-like dyes (eg, 780/60-nm filter).