BDB564325

CD146 Mouse anti-Human, Brilliant Violet 421, Clone: P1H12, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB564325-Each-of-1 In Stock ₹ 28,658.00

BDB564325 - Each of 1

₹ 28,658.00

In Stock

Quantity

1

Base Price: ₹ 28,658.00

GST (18%): ₹ 5,158.44

Total Price: ₹ 33,816.44

Antigen

CD146

Classification

Monoclonal

Conjugate

Brilliant Violet 421

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide

Immunogen

Human Umbilical Vein Cells

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

P1H12

Description

MCAM; MELCAM; MUC18; Gicerin; Melanoma cell adhesion molecule

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The P1H12 monoclonal antibody specifically binds to CD146
  • CD146 is a 118 kDa transmembrane glycoprotein also known as MCAM, MUC18, or Mel-CAM
  • CD146 is a member of the immunoglobulin superfamily and is expressed by angioblasts and mesenchymal stems cells and is strongly expressed by blood vessel endothelium and smooth muscle
  • CD146 is also expressed by melanoma cells, intermediate trophoblasts and a subpopulation of activated T cells
  • The P1H12 monoclonal antibody has been reported to block endothelial cell adhesion that is observed very early in embryogenesis
  • It can be useful in the study of embryologic vasculogenesis
  • This antibody is suitable for immunohistochemical staining of acetone-fixed frozen tissue sections, immunoprecipitation and ELISA
  • The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter)
  • BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.