BDB564533

CD249 Mouse anti-Human, PE, Clone: 2D3/APA, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB564533-Each-of-1 In Stock ₹ 23,451.50

BDB564533 - Each of 1

₹ 23,451.50

In Stock

Quantity

1

Base Price: ₹ 23,451.50

GST (18%): ₹ 4,221.27

Total Price: ₹ 27,672.77

Antigen

CD249

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human Aminopeptidase A Transfected Cell Line

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

2D3/APA

Description

EAP, Aminopeptidase A, Glutamyl aminopeptidase, APA, AP-A, gp160, ENPEP

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The 2D3 monoclonal antibody specifically binds to CD249
  • CD249 is encoded by ENPEP and is also known as Aminopeptidase A (APA/AP-A), Glutamyl aminopeptidase (EAP), and gp160
  • CD249 is expressed by epithelial and endothelial cells in a variety of tissues including those that comprise the proximal tubules and glomeruli of the kidneys
  • It is also expressed by early B-lineage cells and cell lines
  • CD249 belongs to the peptidase M1 family and catalyzes the release of N-terminal glutamate (and to a lesser degree, aspartate) from peptides
  • This ectoenzyme catalyzes the conversion of angiotensin II to angiotensin III which is important in the local regulation of blood pressure
  • It may also play roles in the regulation of angiogenesis and development of B cells.