BDB564724
CD4 Mouse anti-Human, BUV395, Clone: RPA-T4, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564724-Each-of-1 | In Stock | ₹ 41,830.00 |
BDB564724 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,830.00
GST (18%): ₹ 7,529.40
Total Price: ₹ 49,359.40
Antigen
CD4
Classification
Monoclonal
Conjugate
Brilliant Ultraviolet 395
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
RPA-T4
Description
L3T4; T-cell surface antigen T4/Leu-3; W3/25; CD4 antigen (p55)
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The RPA-T4 monoclonal antibody specifically binds to CD4, a 59 kDa single-chain transmembrane glycoprotein that is expressed on T-helper/inducer cell populations
- CD4 is also expressed on thymocytes subsets and at lower levels on monocytes and macrophages
- CD4 functions as a co-receptor in MHC class II-restricted antigen-induced T cell activation and as a receptor for human immunodeficiency viruses (HIV)
- This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80% of thymocytes and 45% of peripheral blood lymphocytes
- RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation
- The antibody was conjugated to BD Horizon BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument
- With an Ex Max at 348nm and an Em Max at 395nm, this dye has virtually no spillover into any other detector
- BD Horizon BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.