BDB564764
CD122 Rat anti-Mouse, PerCP-Cy5.5, Clone: TM-Beta 1, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564764-Each-of-1 | In Stock | ₹ 23,852.00 |
BDB564764 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,852.00
GST (18%): ₹ 4,293.36
Total Price: ₹ 28,145.36
Antigen
CD122
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Il2rb; Il-2Rbeta; IL-2Rβ; IL-15Rbeta; IL-2/15 Receptor-beta; IL-2/15Rbeta
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2b κ
Applications
Flow Cytometry
Clone
TM-Beta 1
Conjugate
PerCP-Cyanine5.5
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide
Immunogen
Mouse IL-2Rβ Transfected Cell Line
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The TM- β 1 antibody reacts with the 90-100-kDa β chain shared by the IL-2 and IL-15 receptors (IL-2R β , CD122)
- In the periphery, CD122 is expressed on CD8+ T lymphocytes, NK cells, NK-T cells, dendritic epidermal T cells, subsets of intraepithelial lymphocytes, and macrophages
- Small subsets of fetal and adult thymocytes constitutively express CD122
- CD122+ cells in the bone marrow include committed NK-cell progenitors
- IL-2R β expression is upregulated by IL-2
- CD122 is a transmembrane glycoprotein of the hematopoietin receptor superfamily which can combine with CD132 ( γc) alone or CD132 plus CD25 (IL-2R α ) to form intermediate or high-affinity IL-2 receptor complexes, respectively
- The β chain of these complexes, CD122, is involved in signal transduction and immunoregulation
- The TM- β 1 antibody blocks high affinity binding of IL-2 or IL-15 to IL-2R β .