BDB564868
Ikaros Mouse anti-Human, Alexa Fluor 647, Clone: R32-1149, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564868-Each-of-1 | In Stock | ₹ 24,341.50 |
BDB564868 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,341.50
GST (18%): ₹ 4,381.47
Total Price: ₹ 28,722.97
Antigen
Ikaros
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide
Immunogen
Human Ikaros Recombinant Protein
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
R32-1149
Description
IKZF1; LYF1; hIk-1; IK1; ZNFN1A1
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The R32-1149 monoclonal antibody specifically binds to Ikaros, which is encoded by IKZF1 (IKAROS family zinc finger 1)
- Ikaros is also known as Lymphoid transcription factor LyF-1 (LYF1) and ZNFN1A1 [Zinc finger protein, subfamily 1A, 1 (Ikaros)]
- Ikaros belongs to the IKAROS family of zinc-finger transcription factors
- This DNA-binding transcription factor forms homodimers and heterodimers with other IKAROS family members
- It is involved in the development of lymphoid tissues and remains abundantly expressed in the thymus and by cells within peripheral lymphoid tissues
- Ikaros functions in the maturation, differentiation, and homeostasis of various hematopoietic cells including T lymphocytes, B cells, NK cells, and neutrophils
- Ikaros regulates the expression of a number of genes including various genes expressed during early stages of B- and T-cell development
- Several alternatively-spliced human Ikaros isoforms have been described
- Abnormal expression of different Ikaros isoforms has been associated with hematologic malignancies
- Flow cytometric analysis of 293F cells transfected with members of the IKAROS family has demonstrated that clone R32-1149 is negative on Helios, Aiolos, and Eos transfectants.