BDB565040
CD62L Mouse anti-Human, Brilliant Violet 711, Clone: SK11, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565040-Each-of-1 | In Stock | ₹ 39,516.00 |
BDB565040 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,516.00
GST (18%): ₹ 7,112.88
Total Price: ₹ 46,628.88
Antigen
CD62L
Classification
Monoclonal
Conjugate
Brilliant Violet 711
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human Peripheral Blood T Lymphocytes
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
SK11
Description
L-selectin; LECAM-1; SELL; LNHR; LSEL; LAM-1; LEU8; PLNHR; TQ-1; MEL-14
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype
IgG2a κ
Related Products
Description
- The SK11 monoclonal antibody specifically binds to CD62L which is also known as, L-selectin, Leukocyte-endothelial cell adhesion molecule 1 (LECAM1/LECAM-1), Leukocyte adhesion molecule 1 (LAM1/LAM-1), Lymph node homing receptor (LNHR), Leu-8, or TQ1
- CD62L is an ∽80 kDa type I transmembrane glycoprotein that belongs to the Selectin/LECAM family
- CD62L is differentially expressed on T cells, B cells, monocytes, granulocytes, and a subset of NK cells
- The CD62L molecule is the human homolog of the mouse lymph node homing receptor, MEL-14
- CD62L plays a role in leucocyte binding to inflamed endothelium and extravasation, as well as mediating lymphocyte homing into peripheral lymphoid tissues through high endothelial postcapillary venules
- Soluble CD62L can result from the proteolytic cleavage of cell surface CD62L during cellular activation or inflammation
- The antibody was conjugated to BD Horizon BV711 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 711-nm
- BD Horizon BV711 can be excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor™ 700-like dyes (eg, 712/20-nm filter)
- Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
- However, the spillover can be corrected through compensation as with any other dye combination.