BDB565140

CD56 Mouse anti-Human, APC-R700, Clone: NCAM16.2, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB565140-Each-of-1 In Stock ₹ 20,737.00

BDB565140 - Each of 1

₹ 20,737.00

In Stock

Quantity

1

Base Price: ₹ 20,737.00

GST (18%): ₹ 3,732.66

Total Price: ₹ 24,469.66

Antigen

CD56

Classification

Monoclonal

Conjugate

APC-R700

Formulation

Aqueous buffered solution containing BSA, protein stabilizer, glycerol, and ≤0.09% sodium azide.

Immunogen

Immunoaffinity-enriched adult human brain NCAM

Quantity

25 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

NCAM16.2

Description

NCAM1; NCAM-1; NCAM; Leu-19; Neural cell adhesion molecule 1; NKH1; MSK39

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

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Description

  • The NCAM16.2 monoclonal antibody specifically binds to human CD56
  • It recognizes an extracellular immunoglobulin-like domain common to 120, 140, and 180 kDa forms of CD56, also known as the neural cell adhesion molecule (NCAM), NKH1 or MSK39
  • The CD56 antigen is expressed on approximately 10% to 25% of peripheral blood lymphocytes
  • It is present on essentially all resting and activated CD16+ natural killer (NK) lymphocytes and approximately 5% of CD3+ peripheral blood lymphocytes
  • CD3+ CD56+ T lymphocytes comprise a unique subset of cytotoxic T lymphocytes that mediates non-major histocompatibility complex (MHC)-restricted cytotoxicity
  • CD56 antigen density on NK lymphocytes increases upon cellular activation
  • The CD56 antigen is involved in neuronal homotypic cell adhesion and cell differentiation during embryogenesis
  • CD16+ CD56+ NK cells demonstrate reciprocal transfer of an activation state with dendritic cells
  • This antibody was conjugated to BD Horizon APC-R700, which has been developed exclusively by BD Biosciences as a better alternative to Alexa Fluor™ 700
  • APC-R700 excites and emits at similar wavelengths to Alexa Fluor™ 700 yet exhibits significantly improved brightness
  • This dye can be excited by the red laser and detected with the same filter set as Alexa Fluor™ (eg, 730/45-nm filter).