BDB565168
TIGIT Mouse anti-Mouse, PE, Clone: 1G9, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565168-Each-of-1 | In Stock | ₹ 32,707.50 |
BDB565168 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,707.50
GST (18%): ₹ 5,887.35
Total Price: ₹ 38,594.85
Antigen
TIGIT
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Tigit; Vstm3; T cell immunoreceptor with Ig and ITIM domains
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
1G9
Conjugate
PE
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide
Immunogen
Mouse TIGIT Recombinant Protein
Quantity
0.1 mg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The 1G9 monoclonal antibody specifically binds to T cell immunoreceptor with Ig and ITIM domains (TIGIT) which is also known as, V-set and transmembrane domain-containing protein 3 (Vstm3)
- TIGIT is a 26 kDa, type I transmembrane glycoprotein that belongs to the poliovirus receptor (PVR) family
- TIGIT is expressed on activated and memory CD4+ T cells and CD8+ T cells, follicular T helper cells, regulatory T cells, and NK cells
- Its ligands include the poliovirus receptor (PVR, aka, CD155), poliovirus receptor-related protein 2 (PVRL2, aka, CD112), and poliovirus receptor-related protein 3 (PVRL3, CD113)
- TIGIT functions as a negative regulator of T cell and NK cell responses including proliferation, cytotoxicity, and the production of proinflammatory cytokines
- TIGIT-deficient mice are reportedly more susceptible to developing autoimmune diseases in certain model systems.