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BDB565805

CD11c Mouse anti-Human, Unlabeled, Clone: 3.9, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB565805-Each-of-1 In Stock ₹ 12,157.40

BDB565805 - Each of 1

₹ 12,157.40

In Stock

Quantity

1

Base Price: ₹ 12,157.40

GST (18%): ₹ 2,188.332

Total Price: ₹ 14,345.732

Antigen

CD11c

Classification

Monoclonal

Concentration

0.5mg/mL

Description

ITGAX; AlphaX Integrin; Axb2; Integrin alpha-X; CR4; SLEB6; p150,95 alpha

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human, Rhesus Monkey

Isotype

IgG1 κ

Applications

Flow Cytometry, Immunofluorescence

Clone

3.9

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human monocytes and synovial cells

Quantity

0.1 mg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Description

  • The 3.9 monoclonal antibody specifically binds to CD11c, which is also known as Integrin alpha X ( α X Integrin/ITGAX), or p150,95 Integrin alpha chain
  • CD11c is a ∽150 kDa type I transmembrane glycoprotein
  • It is expressed on monocytes, macrophages, granulocytes, NK cells, dendritic cells, and subsets of B and T cells
  • It associates with CD18 (Integrin beta 2/ β 2 Integrin) to form the CD11c/CD18 complex, which is also known as p150,95 Integrin, or the Type 4 Complement Receptor (CR4)
  • CD11c/CD18 binds fibrinogen and reportedly serves as a receptor for iC3b and ICAM-1/CD54
  • CD11c/CD18 functions as an adhesion molecule that mediates cellular binding to ligands expressed on stimulated epithelium and endothelium
  • The 3.9 monoclonal antibody crossreacts with Rhesus macaque leucocytes.