BDB566354

TRIF (TICAM-1) Mouse anti-Human, PE, Clone: U19-709, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB566354-Each-of-1 In Stock ₹ 26,166.00

BDB566354 - Each of 1

₹ 26,166.00

In Stock

Quantity

1

Base Price: ₹ 26,166.00

GST (18%): ₹ 4,709.88

Total Price: ₹ 30,875.88

Antigen

TRIF (TICAM-1)

Clone

U19-709

Conjugate

PE

Gene Alias

TICAM1, PRVTIRB, MyD88-3, IIAE6

Immunogen

Human TRIF Recombinant Protein

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Related Products

Img

BD Biosciences

BDB742775

--

Img

BD Biosciences

BDB742724

--

Img

BD Biosciences

BDB742412

--

Img

BD Biosciences

BDB742416

--

Img

BD Biosciences

BDB742856

--

Img

BD Biosciences

BDB743240

--

Img

BD Biosciences

BDB566359

--

Img

BD Biosciences

BDB743416

--

Description

  • The U19-709 monoclonal antibody specifically recognizes TIR domain-containing adapter inducing IFN-β (TRIF),which is also known as TIR domain-containing adapter molecule 1 (TICAM-1)
  • TRIF (TICAM-1) is an intracellular adaptor protein that contains a Toll/Interleukin-1 Receptor (TIR) homology domain
  • Double stranded RNA (dsRNA)-bound Toll-like receptor 3 (TLR3/CD283) or lipopolysaccharide (LPS)-triggered TLR4/CD284 can interact with TRIF (TICAM-1)
  • This leads to downstream signaling cascades involving Interferon regulatory factors (eg, IRF3 or IRF7) or nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) that induce Interferon-beta (IFN-β) expression
  • R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae
  • It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule
  • This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.