BDB569184

CD4 Mouse anti-Human, RB545, Clone: SK3 (also known as Leu3a), BD Horizon™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB569184-Each-of-1 In Stock ₹ 13,590.30

BDB569184 - Each of 1

₹ 13,590.30

In Stock

Quantity

1

Base Price: ₹ 13,590.30

GST (18%): ₹ 2,446.254

Total Price: ₹ 16,036.554

Antigen

CD4

Classification

Monoclonal

Conjugate

RB545

Gene Alias

L3T4; Leu3a; T-cell surface antigen T4/Leu-3 ; W3/25 ; CD4 antigen (p55)

Immunogen

Human Peripheral Blood T Cells

Quantity

25 Tests

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Excitation/Emission

Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications

Flow Cytometry

Clone

SK3 (also known as Leu3a)

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Gene ID (Entrez)

920

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype

IgG1 κ

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Description

  • The SK3 monoclonal antibody specifically binds to CD4
  • The CD4 antigen is a 55 kDa type 1 transmembrane glycoprotein that belongs to the immunoglobulin superfamily
  • It is expressed on T-helper/inducer lymphocytes and monocytes
  • CD3+CD4+ T cells comprise approximately 28% to 58% of normal peripheral blood lymphocytes
  • CD4 is also expressed on 80% to 95% of normal thymocytes
  • The CD4 antigen is present in low density on the cell surface of monocytes and in the cytoplasm of monocytes and macrophages (CD3-CD4+)
  • CD4 serves as a T cell coreceptor for MHC class II antigen recognition and as a receptor for the human immunodeficiency virus (HIV)
  • The SK3 antibody inhibits HIV binding to CD4+ cells
  • CD4 Monoclonal antibody specifically detects CD4 in Human samples
  • It is validated for Flow Cytometry