BDB610724
Rab5 Mouse, Unlabeled, Clone: 1, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB610724-Each-of-1 | In Stock | ₹ 25,587.50 |
BDB610724 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,587.50
GST (18%): ₹ 4,605.75
Total Price: ₹ 30,193.25
Antigen
Rab5
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Human Rab5 aa. 1-215
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Canine, Human
Isotype
IgG2a
Applications
Western Blot
Clone
1
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Related Products
Description
- Rab5 is a low molecular weight GTP-binding protein that plays a role in endocytic vesicle traffic
- Like other Rab proteins, Rab5 has C-terminal cysteine residues that are post translationally modified by geranylgeranylation which is critical for its membrane targeting
- Rab5 is associated with early endosome and plasma membranes and evidence suggests that Rab5 regulates early endosome fusion
- The GTP/GDP cycle controls shuttling of Rab proteins between the cytosol and membranes
- In vitro, Rab5 proteins are removed from membranes by a GDP dissociation inhibitor protein (rabGDI) which leads to the formation of a cytosolic Rab5-rabGDI complex
- Rab5 may insert into membranes by a multistep process in a which a transient GDP-Rab5 intermediate is formed and converted into GTP-Rab5 that subsequently enters the acceptor membrane and releases rabGDI into the cytosol
- Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting